It was first published in 1953 and ran till 1985, with 259 issues released. The last issue was not distributed till 1991. Yandro began life as the organ of the Eastern Indiana Science Fiction Association, originally called EISFA and edited by Juantia Wellons (before becoming Juantia Coulson) and Beverly Amers (;ater Beverly DeWeese). The Coulsons married in 1953, and Robert "Buck" Couson, began doing book reviews for the zine. By the late 1950s the name had been changed to Yandro derived from an old folk song in a Manly Wade Wwellman story.
Yandro featured fiction, articles and reviews of books and fanzines.
Contributions of writing included George Barr, John Brunner, L. Sprague de Camp, E.J. Carnell, R.L. Clancy, Alan Dodd (Camber), Dennis Lien, Dave Locke, Allen Mardis, Alexei Panshin, Seth Poole, Jerry Pournelle, Gene Roddenberry, George Scithers, Robert Silverberg (Spaceship), Don and Maggie Thompson (Comic Art), Bjo Trimble, Bob Tucker (Le Zombie), Ted White, Gene Wolfe, and Roger Zelazny.
Contributions of art work came from Dan Adkins, George Barr, Sherna Burley, Jim Cawthorn, Richard Delap, Richard Flinchbaugh, George Foster, Robert Gilbert, Alexis Gilliland, Jay Kinney, David lewton, Dave Prosser, Bill Rotsler, Dick Schultz, Randy Scott, Reg Smith, Mike Symes, Arthur Thomson.
Covers were by Herb Beach, Jim Cawthorn, Robert E. Gilbert, Cynthia Goldstone, Taral Wayne (DNQ), and the Yandro logo was by Arthur Thomson.
Letters came from Philip Jose Farmer, Fredric Wertham.
Yandro won the Hugo Award for Best Fanzine in 1965. It was nominated every year form 1958 to 1967.